Angelalign Technology Inc., Zhaoke Medical Holdings Ltd., Dentium, and others release financial reports; Topchoice Medical plans to acquire an ophthalmic company for 600 million yuan; United States to allow dental hygienists to practice independently in hospitals...

Angelalign Technology Inc. 2025 Performance: Annual Case Volume Reaches 532,400, Achieving Growth in Both Chinese and Global Markets

On March 27, 2026, Angelalign Technology Inc. released its 2025 annual results announcement. The annual clear aligner therapy case volume reached 532,400, a year-on-year increase of 48.1%, with revenue of $370.3 million, up 37.8% year-on-year. Among these, the global market contributed 256,200 cases and revenue of $163.0 million, an increase of 102.5%; the Chinese mainland market contributed 276,200 cases and revenue of $207.3 million, an increase of 10.1%. The company's cumulative total case volume has exceeded 2 million.

Regarding products, the global clinical usage of the AngelButton solution has surpassed 100 million times, and the A6 Mandibular Advancement solution has undergone 10 years of clinical iteration. In 2025, the company introduced new technologies for complex adult cases, such as the Angel Curved Guide Plate and Angel Occlusal Lock Guide Plate. The orthodontic design platform iOrtho continues to iterate on a bi-weekly basis. CEO Hu Jiezhang stated that Angelalign will continue to rely on its open corporate culture to attract diverse global talent, focusing on shared medical goals to create excellent products and services.

Topchoice Medical Plans 600 Million Yuan Acquisition of Eye Care Companies, to Establish Eye Care Zones Within Dental Hospital Network

On March 24, 2026, Topchoice Medical Co., Ltd. announced its intention to acquire 100% equity in Hangzhou Cunji Glasses Co., Ltd., Ningbo Guangji Eye Care Technology Co., Ltd., Hangzhou Guangji Eye Care Technology Co., Ltd., and Xinchang Guangji Glasses Co., Ltd. using its own funds of 600 million yuan (600 million). The four companies involved in this acquisition are all directly or indirectly controlled by Zhejiang Topchoice Eye Hospital Investment Management Co., Ltd., whose actual controller is Lu Jianming, making this transaction a connected transaction. According to the announcement, Hangzhou Cunji Glasses' 2025 revenue was 152.8827 million yuan, with a net profit of 55.5848 million yuan; Ningbo Guangji Eye Care Technology Co., Ltd.'s 2025 revenue was 455,200 yuan, with a net loss of 72,000 yuan; Hangzhou Guangji Eye Care Technology Co., Ltd. has not conducted actual business; Xinchang Guangji Glasses Co., Ltd.'s 2025 revenue was 1.0118 million yuan, with a net loss of 77,500 yuan. After the transaction is completed, Topchoice Medical plans to establish eye care zones within its existing dental hospital network to enhance operational efficiency and synergistic value. This transaction still requires approval at the shareholders' meeting.

Zhaoke Medical Holdings Ltd. 2025 Annual Report: Dental Revenue Reaches 170 Million Yuan, Up Approximately 14.5% Year-on-Year

In 2025, Zhaoke Medical Holdings Ltd.'s annual revenue reached 1.065 billion yuan, a year-on-year increase of 11.1%; net profit was 135 million yuan, up 63.8% year-on-year. Among this, dental business revenue reached 170 million yuan, an increase of 14.5% year-on-year, with 153,611 patient visits, an average fee per visit of 1,106 yuan, and a penetration rate of 36.7%. The company stated that the performance growth benefited from improved operational efficiency and enhanced economies of scale. The combined revenue of three central-type facilities in Shenzhen Bay, Guangzhou Jinsui Road, and Chengdu High-tech Zone reached 377 million yuan, a year-on-year increase of 131.1%. As of the end of 2025, the number of full-time doctors increased to 399, with an annual turnover rate of 2.9%.

Kaisa Health 2025 Annual Report: Dental Business Revenue 132 Million HKD, Down 26.2% Year-on-Year

In 2025, Kaisa Health Group's total revenue was 139 million HKD, a year-on-year decrease of 25%, with a net loss attributable to shareholders of the parent company of 46.678 million HKD. Dental business revenue was 132 million HKD, a decrease of 26.2% year-on-year, primarily affected by the Chinese government's VBP policy, leading to a decline in product prices. The company's gross profit decreased from 81.858 million HKD to 50.644 million HKD, with the gross profit margin dropping to 36.4%. As of December 31, 2025, the company's cash balance was approximately 110 million HKD, with a current ratio of 3.98, indicating a sound asset-liability structure. The company plans to acquire Chongxing Limited for 21.604 million RMB to enter the field of anesthesia and psychotropic drug manufacturing.

Dentium: 2025 Net Profit Attributable to Shareholders of the Parent Company Drops 77.43%, Operating Profit Falls Over 30%

On March 23, 2026, Dentium submitted its 2025 annual audit report, showing a net profit attributable to shareholders of the parent company of 16.411 billion KRW, a year-on-year decrease of 77.43%, and operating profit decreased by 34.91%. The consolidated revenue for the 2025 fiscal year was 346.452 billion KRW, a decrease of 15.05% compared to the previous year. Dentium faces challenges in the Chinese market, with revenue dropping 42% in Q3 2025; the company plans to respond by strengthening its localization strategy. Additionally, Dentium faces governance uncertainties, as the activist fund Align Partners has filed a lawsuit against it, demanding a review of the legality of the annual general meeting. As of the end of the 2025 fiscal year, Dentium's total assets were 932.790 billion KRW, with an asset-liability ratio of approximately 39.8%.

NMPA Releases 4 Dental Medical Device Industry Standards, Covering Root Canal, Additive Manufacturing, and Other Fields

On March 9, 2026, the National Medical Products Administration (NMPA) announced the official release of 26 medical device industry standards, covering fields such as dental prosthetics, tooth whitening, and medical additive manufacturing. Among them, the revised "Dentistry — Root Canal Posts" (YY/T 0517—2026) and "Dentistry — External Tooth Bleaching Products" (YY/T 0825—2026) will be formally implemented, and relevant enterprises must adjust their production processes and quality systems by March 1, 2027. Furthermore, the new standard "Medical Additive Manufacturing — Polyetheretherketone Powder for Powder Bed Fusion" (YY/T 2008—2026) fills a standard gap in the field of dental and orthopedic additive manufacturing, while "Test Method for In Vitro Degradation of Degradable Magnesium-based Metal Implants" (YY/T 2009—2026) provides a basis for in vitro degradation determination.

U.S. to Allow Dental Hygienists to Practice Independently in Hospitals Without Direct Dentist Supervision

On March 12, 2026, Utah Governor Spencer Cox signed the Dental Hygienist Amendments (HB 414), which will take effect statewide on May 6, 2026, allowing dental hygienists to practice independently in hospitals without dentist supervision. The bill expands the professional autonomy of dental hygienists, aiming to improve access to oral hygiene services for hospitalized patients and reduce systemic health risks caused by oral issues. Hospitals can directly hire or collaborate with dental hygienists to conduct oral health management based on operational needs. Relevant institutions are advised to adjust internal processes before the bill's effective date to ensure smooth implementation.

CareQuest and Kno2 Form Strategic Partnership to Advance Integration of Dentistry into U.S. Health Information Exchange System

CareQuest Innovation Partners and Kno2 announced a strategic partnership to launch a national initiative integrating dentistry into the U.S. core health information exchange infrastructure. The two platforms cover approximately 20% of the dental market, with plans to launch within 6 months, aiming for a 25% adoption rate among EDR-end healthcare provider users in the first year. Kno2 processes billions of data transactions annually. Kno2 founder and president Therasa Bell stated that with strengthened federal interoperability compliance requirements and rising healthcare costs, there is an urgent need to fully integrate dentistry into a connected healthcare ecosystem.

Orca Dental AI Receives New FDA Clearance, Its CephX Becomes the Only Orthodontic AI Diagnostic Platform with 2D+3D FDA Certification

On March 24, 2026, Orca Dental AI announced that its CephX platform received FDA 510(k) clearance for 3D imaging, making it the only orthodontic AI diagnostic support company with dual 2D+3D certification, already applied in 180 countries. The platform's CEPHX3D system features AI-driven automatic segmentation of the mandible, maxilla, full dentition, and inferior alveolar nerve, and is equipped with a web-based interactive 3D viewer for linear, angular, and volumetric measurements. Simultaneously, Orca Dental AI announced strategic integrations with the DEXIS brand and Greyfinch, enabling AI-driven cephalometric analysis and diagnostic automation within imaging workflows.

In Response to CRA's Strict Scrutiny of Employee Classification, Dental Staffing Platform Fairly Staffing Launches Industry-First Compliant Payroll Management System

On March 24, 2026, dental staffing platform Fairly Staffing announced a partnership with Nmbr to launch the dental industry's first integrated compliant payroll management system. The system can automatically calculate payroll deductions, remit CPP, EI, and income tax to the CRA, and generate compliant documentation. It already serves over 600 dental clinics in Canada, helping them reduce tax compliance risks.

PDS Health Deploys Electronic Health Record System at University of the Pacific School of Dentistry and Medical Collaboration Center

On March 23, 2026, PDS Health Technologies announced a partnership with the University of the Pacific. The university's School of Dentistry will deploy the Epic® electronic health record system, covering three clinical scenarios: dental, medical, and outpatient surgery centers, making it the first dental school in the U.S. to deploy this system. The system already supports over 14 million patients across more than 1,250 healthcare sites globally. This collaboration aims to enhance clinical teaching collaboration and improve referral efficiency. PDS Health will also provide revenue cycle management services to improve financial performance. As of publication, specific financial details of the implementation have not been disclosed by either party.

UK NHS Dental Satisfaction Drops to 22%: Scottish Model Satisfaction Doubles, May Drive UK-Wide Contract Reform

UK think tank The King's Fund released the "2025 NHS and Social Care Public Satisfaction Report," showing that overall NHS dental satisfaction in the UK has fallen to 22%, with Scotland at 40%, England at 21%, and Wales at 14%; the survey covered 1,460 respondents, with 54% dissatisfied. The English government confirmed that starting April 2026, NHS dental contractors must allocate 8.2% of their contract value to urgent care, with 11 urgent courses per £10,000, and urgent care payments set at £75. The Welsh government announced that starting April 1, 2026, it will abolish the UDA model in favor of an hourly rate system, with dentists' hourly pay increasing to £150.

California to Restrict Dental Care Scope for Undocumented Immigrants Under Medicaid, Expected to Save Over $300 Million Annually

Starting July 1, 2026, California will restrict the scope of Medicaid dental care for undocumented immigrants aged 19 to 54, limiting affected individuals to emergency dental services only. This policy, part of last year's approved California budget, is expected to save the state approximately $308 million annually, with projected annual savings increasing to $336 million in future years. In the San Joaquin Valley, approximately 156,000 undocumented immigrants gained Medicaid eligibility through the expansion policy, with Madera County having the highest proportion affected at 17.2%; Kern County has the highest number of affected individuals, totaling 36,673. The California Dental Association warns that funding cuts will lead vulnerable populations to forgo or delay basic oral care, potentially causing a surge of dental emergencies in hospital emergency departments.

Beijing News Investigation: 17 Probiotic Oral Care Products Contain No Live Bacteria, Some Questioned for Illegally Claiming to Prevent/Treat H. pylori

On March 23, 2026, the Beijing News published a special investigation revealing compliance risks in popular oral care products on the market that claim to contain probiotics. Among 18 randomly selected products claiming to contain probiotic ingredients, 17 did not contain live probiotic bacteria, mostly using inactivated "postbiotics." Brands involved in the investigation include sakose, Dr. Dio, Hao Chi Jian, Yunnan Baiyao, Lion, Nice, Saky, and others. Some brands even illegally claimed to "inhibit or eradicate Helicobacter pylori" and circumvented regulation by registering as "disinfection products" or "medical devices." The NMPA has previously stated there is no evidence that brushing teeth can affect gastric H. pylori. The "Toothpaste Supervision and Management Measures" implemented on December 1, 2023, also prohibit toothpaste from explicitly or implicitly claiming medical effects.

Shanghai Research Team Develops Whitening Tooth Powder, Achieving Nearly 50% Increase in Tooth Whiteness After 12 Hours of Use

In January 2026, a team including the Shanghai Institute of Ceramics, Chinese Academy of Sciences, developed an experimental whitening tooth powder (BSCT ceramic powder) activated by electric toothbrush vibration, capable of whitening while repairing damaged enamel and dentin. Experiments showed that after 12 hours of brushing with the powder using an electric toothbrush, the whiteness of teeth in the experimental group was nearly 50% higher compared to the control group brushed with saline. The technology is based on the "piezoelectric effect," catalyzing the production of reactive oxygen species during brushing to decompose organic staining molecules on the tooth surface. Although the technology is currently in the experimental stage, researchers believe it holds promise for providing safe and convenient solutions for future at-home oral health care.

New Study: Gum Disease-Related Bacteria May Accelerate Breast Tumor Initiation and Progression

On March 19, 2026, researchers from the Johns Hopkins Kimmel Cancer Center and the Bloomberg Kimmel Institute for Cancer Immunotherapy published a study showing that Fusobacterium nucleatum, a bacterium associated with gum disease, may enter breast tissue via the bloodstream, promoting or accelerating the initiation and progression of breast tumors. The study found that this bacterium accelerated tumor growth in animal models and increased the risk of cancer cell metastasis to the lungs, particularly breast cancer cells carrying BRCA1 mutations showed higher sensitivity to it. The study further suggests that oral microbes may be an environmental trigger for breast cancer risk, requiring validation through clinical trials.

New Study: AI-Generated X-rays Can Deceive Radiologists, Identification Accuracy as Low as 41%

A research team from the Icahn School of Medicine at Mount Sinai, New York, published a study in Radiology, finding that radiologists' accuracy in identifying AI-generated X-rays was only 41%. The study tested 264 X-ray images, involving 17 doctors from 12 institutions across 6 countries. When doctors were informed about the existence of synthetic images, their identification accuracy improved to 75%. The identification accuracy of AI models ranged between 57% and 85%. The study recommends embedding invisible watermarks and encrypted signatures at the time of image capture to verify source authenticity, calling for the establishment of digital protection mechanisms to address deepfake risks.

New Study: Periodontitis Pathogen Possesses "Genetic Brake," Holds Promise for Precise Microbiome-Preserving Treatment

Research from the University of Florida shows that the periodontitis pathogen Porphyromonas gingivalis carries a "genetic brake" called CRISPR array 30.1. By targeting this mechanism, it may be possible to precisely inhibit periodontitis progression without disrupting oral microbiome balance. The study found that after deleting this array, mutant strains produced twice the amount of biofilm compared to wild-type strains. Furthermore, in a Galleria mellonella infection model, the mutant strain induced 50% mortality in just 130 hours, compared to 200 hours for the wild-type. The study notes that periodontitis affects approximately 42% of people over 30 in the U.S., causing economic losses exceeding $150 billion annually. The research was funded by the National Institutes of Health, and future precision therapies may utilize engineered phages for targeted treatment.